Key result
HIV-positive individuals with undetectable viral load on antiretroviral therapy and low cardiovascular risk showed no significant difference in mean carotid intima-media thickness compared to uninfected controls.
Why the study?
Few studies have observed the occurrence of cardiovascular diseases and carotid thickness in people living with HIV who have low cardiovascular risk and undetectable viral load.
Does well-controlled HIV infection on ART without protease inhibitors increase carotid intima-media thickness and inflammatory biomarkers compared to healthy controls in a low cardiovascular risk population?
Cross-Sectional (n=115)
No
Does well-controlled HIV infection on ART without protease inhibitors increase carotid intima-media thickness and inflammatory biomarkers compared to healthy controls in a low cardiovascular risk population?
Absolute Event Rate: 0.573% vs 0.586%
p-value: p=0.697
HIV-positive individuals with undetectable viral load on ART without protease inhibitors and at low cardiovascular risk do not have increased carotid thickness compared to uninfected controls.
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Leite et al. (2020) conducted a cross-sectional in HIV infection with low cardiovascular risk (n=115). HIV infection under ART with undetectable viral load vs. Healthy non-HIV infected individuals was evaluated on Mean carotid intima-media thickness (mm) (p=0.697). HIV-positive individuals with undetectable viral load on antiretroviral therapy and low cardiovascular risk showed no significant difference in mean carotid intima-media thickness compared to uninfected controls.
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