Key result
In patients with trigger-driven atrial fibrillation, enabling preventive pacing algorithms significantly reduced median AF burden from 2.06 to 1.49 hours/day (P=0.03304).
Why the study?
Does individualized selection of preventive pacing algorithms reduce AF burden in patients with AF and a pacemaker indication?
Population
126 patients with at least one documented atrial fibrillation episode and a conventional antibradycardia…
Comparison
Individualized preventive pacing algorithms… vs Conventional pacing during a 3-month Diagnostic…
Design
Cohort
Follow-up
3-month Therapeutic Phase
Authors
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Supports individualized preventive pacing in trigger-driven AF; leaves open confirmation in randomized trials.
Does individualized selection of preventive pacing algorithms reduce AF burden in patients with AF and a pacemaker indication?
Effect estimate: 28% improvement
Absolute Event Rate: 1.49% vs 2.06%
p-value: p=0.03304
Individualized selection of preventive pacing algorithms based on diagnostic data reduces AF burden specifically in patients whose AF is triggered by premature atrial contractions.
Lewalter et al. (2006) studied Atrial fibrillation (n=126). Preventive pacing algorithms vs. Conventional pacing (Diagnostic Phase) was evaluated on AF burden (28% improvement, p=0.03304). In patients with trigger-driven atrial fibrillation, enabling preventive pacing algorithms significantly reduced median AF burden from 2.06 to 1.49 hours/day (P=0.03304).
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