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August 19, 2022National Journal of Physiology Pharmacy and PharmacologyOpen Access

Correlation of oxidative stress and metabolic risk factors in apparently healthy adults

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Key result

Adults with metabolic risk factors had significantly higher hsCRP (4783.1 vs 1640.5) and lower serum GSH (3.17 vs 4.79) compared to those without risk factors, indicating greater oxidative stress.

Why the study?

Risk factors of metabolic syndrome are associated with increased inflammation, prompting an evaluation of the correlation between oxidative stress and metabolic risk factors in apparently healthy adults.

Are metabolic risk factors associated with increased oxidative stress markers (hsCRP and GSH) in apparently healthy adults?

Population

120 apparently healthy adults

Design

Cross-sectional study

Authors

APAlok K. PalIndian Space Research OrganisationAPAmar PatelFlorida State UniversityVGVandana GuptaSam Higginbottom Institute of Agriculture

Discussion

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Implication

Should not yet change practice; hypothesis-generating for oxidative stress interventions in metabolic risk.

Study Design

Type

Cross-Sectional (n=120)

Structured PICO

Are metabolic risk factors associated with increased oxidative stress markers (hsCRP and GSH) in apparently healthy adults?

P
Population
120 apparently healthy Indian adults, categorized by the presence of metabolic risk factors, assessed for oxidative stress markers.
C
Comparator
Adults without any metabolic risk factors (n=43)
O
Outcome
Serum levels of hsCRP and serum GSHsurrogate

Cite This Study

Pal et al. (2022) conducted a cross-sectional in Metabolic risk factors (n=120). Metabolic risk factors vs. No metabolic risk factors was evaluated on Serum levels of hsCRP and GSH. Adults with metabolic risk factors had significantly higher hsCRP (4783.1 vs 1640.5) and lower serum GSH (3.17 vs 4.79) compared to those without risk factors, indicating greater oxidative stress.

synapsesocial.com/papers/6a6f27b8febe604dd7082a6dhttps://doi.org/10.5455/njppp.2023.13.08382202205082022
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