Population
Duck hepatitis B virus mutants
Comparison
Frameshift or stop codon mutations in a portion… vs Wild type duck hepatitis B virus
Design
Preclinical
Authors
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Partial pol activity in animal hepadnavirus models; leaves open minimal functional domains and human therapeutic relevance.
The study provides evidence that less-than-full-length pol gene products in hepadnaviruses can be functional in viral DNA synthesis.
Wu et al. (1991) studied this question.
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