Key result
Major depression was associated with high degrees of dependence and lower quality of life across all domains in elderly patients with cardiovascular disease.
Cross-Sectional (n=1,020)
No
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In elderly patients with cardiovascular disease, non-cardiovascular comorbidities, particularly depression, are the primary clinical determinants of dependence and reduced quality of life.
BACKGROUND: The aging process promotes a progressive increase in chronic-degenerative diseases. The effect of these diseases on the functional capacity has been well recognized. Another health parameter concerns "quality of life related to health". Among the elderly population, cardiovascular diseases stand out due to the epidemiological and clinical impact. Usually, these diseases have been associated with others. This set of problems may compromise both independence and quality of life in elderly patients who seek cardiologic treatment. These health parameters have not been well contemplated by cardiologists. OBJECTIVE: Evaluating, among the elderly population with cardiovascular disease, which are the most relevant clinical determinants regarding dependence and quality of life. METHODS: This group was randomly and consecutively selected and four questionnaires were applied: HAQ, SF-36, PRIME-MD e Mini Mental State. RESULTS: The study included 1,020 elderly patients, 63.3% women. The group had been between 60 and 97 years-old (mean: 75.56 ± 6.62 years-old). 61.4% were independent or mild dependence. The quality of life total score was high (HAQ: 88.66 ± 2.68). 87.8% of patients had a SF-36 total score > 66. In the multivariate analysis, the association between diagnoses and high degrees of dependence was significant only for previous stroke (p = 0.014), obesity (p < 0.001), lack of physical activity (p = 0.016), osteoarthritis (p < 0.001), cognitive impairment (p < 0.001), and major depression (p < 0.001). Analyzing the quality of life, major depression and physical illness for depression was significantly associated with all domains of the SF-36. CONCLUSION: Among an elderly outpatient cardiology population, dependence and quality of life clinical determinants are not cardiovascular comorbidities, especially the depression.
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Rodrigues et al. (2015) conducted a cross-sectional in Cardiovascular disease (n=1,020). Major depression vs. Absence of major depression was evaluated on High degree of dependence (HAQ score ≥ 1.5) (OR 2.76, 95% CI 1.86-4.10, p=<0.001). Major depression was associated with high degrees of dependence and lower quality of life across all domains in elderly patients with cardiovascular disease.
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