Osteoporosis Telephonic Intervention to Improve Medication Regimen Adherence
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Discussion
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Implication
Randomized trial reveals telephone counseling does not significantly improve medication adherence in older adults with osteoporosis, suggesting standard educational materials may be equally effective.
Key Points
- To assess whether a telephone-based counseling intervention using motivational interviewing improves medication adherence among older adults newly prescribed osteoporosis treatment.
- Conducted a 1-year randomized controlled trial enrolling Medicare beneficiaries newly prescribed an osteoporosis medication via a pharmacy benefits manager.
- Randomized participants to either telephone counseling rooted in motivational interviewing (n = 1046) or mailed educational materials (n = 1041).
- Assessed medication regimen adherence as the primary endpoint using the median medication possession ratio over 1 year of follow-up in an intention-to-treat analysis.
- Median adherence was 49% (interquartile range, 7%–88%) in the intervention arm versus 41% (interquartile range, 2%–86%) in the control arm (P = .07 by Kruskal-Wallis test).
- Observed no statistically significant differences between groups in self-reported fracture rates during the 1-year follow-up.
Cite This Study
Daniel H. Solomon (2012) studied this question.