Key result
Current smoking significantly increased the risk of incident hypertension in normal weight individuals (HR 1.119), particularly females, but had no significant effect in overweight or obese populations.
Why the study?
Little was known about how the interaction effect between obesity and current smoking affected the incidence of hypertension.
Does current smoking increase the incidence of hypertension in Chinese adults, and is this effect modified by BMI?
Population
12,900 subjects in a Chinese cohort
Comparison
Current smoking vs non-current smoking across BMI categories
Design
Cohort study
Follow-up
22-year
Authors
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Hypothesis-generating for weight-specific hypertension prevention; should not yet change clinical practice pending confirmatory trials.
Cohort (n=12,900)
Yes
Does current smoking increase the incidence of hypertension in Chinese adults, and is this effect modified by BMI?
Hazard Ratio: 1.119 (95% CI 1.013–1.236)
p-value: p=0.027
Current smoking increases the risk of incident hypertension primarily in normal-weight individuals, particularly females and middle-aged adults, but not in overweight or obese individuals.
Yao et al. (2020) conducted a cohort in Hypertension (n=12,900). Current smoking vs. Nonsmoking was evaluated on Incidence of hypertension in normal weight subjects (HR 1.119, 95% CI 1.013-1.236, p=0.027). Current smoking significantly increased the risk of incident hypertension in normal weight individuals (HR 1.119), particularly females, but had no significant effect in overweight or obese populations.
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