In vitro effect of MD805 and low molecular weight heparin (LMWH) on increased levle of platelet binding IgG in patient with heparin induced thrombocytopenia (HIT).

Platelet binding IgG (PBIgG) in plasma from a patient with HIT measured with an elevation by the addition of unfractionated heperin rather than LMWH, and the elevation of PBIgG could be suppressed with MD805. It was suggested that both drugs might exert suppressible effect on IgG binding to platelet in patient with HIT.