Key result
Early initiation of extracorporeal cardiac shock wave therapy 3 days after acute myocardial infarction in pigs significantly improved left ventricular ejection fraction (42% vs 32%, P<0.001).
Why the study?
Does extracorporeal cardiac shock wave therapy improve left ventricular remodeling in a pig model of acute myocardial infarction?
Population
Pigs with acute myocardial infarction created by surgically excising the proximal segment of the left…
Comparison
Low-energy extracorporeal cardiac shock wave… vs Same procedure without shock wave treatment
Design
Preclinical
Authors
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Does not support clinical adoption post-MI; hypothesis-generating for remodeling and requires human trials.
Does extracorporeal cardiac shock wave therapy improve left ventricular remodeling in a pig model of acute myocardial infarction?
Absolute Event Rate: 42% vs 32%
p-value: p=<0.001
Low-energy extracorporeal cardiac shock wave therapy improves left ventricular remodeling and angiogenesis when initiated early after acute myocardial infarction in a porcine model.
Uwatoku et al. (2007) studied Acute myocardial infarction (n=20). Extracorporeal cardiac shock wave therapy vs. No shock wave treatment was evaluated on Left ventricular ejection fraction (early treatment protocol) (p=<0.001). Early initiation of extracorporeal cardiac shock wave therapy 3 days after acute myocardial infarction in pigs significantly improved left ventricular ejection fraction (42% vs 32%, P<0.001).
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