Key result
Shock wave therapy linked to ~9% LVEF improvement and symptom relief in a case report.
Why the study?
PCI and CABG do not necessarily guarantee recovery of post-procedure LV dysfunction or symptom relief, and no definitive effective method exists to enhance microcirculation.
Does shock wave therapy improve symptoms and cardiac remodeling in a patient with ischemic cardiomyopathy?
Case Report (n=1)
Does shock wave therapy improve symptoms and cardiac remodeling in a patient with ischemic cardiomyopathy?
Cardiac shock wave therapy may improve LVEF, cardiac remodeling, and symptoms in patients with ischemic cardiomyopathy and refractory angina unsuitable for revascularization.
Shock wave therapy may aid refractory post-revascularization LV dysfunction; hypothesis-generating and requires prospective trials before adoption.
Percutaneous coronary intervention (PCI) and coronary-artery bypass grafting (CABG) are two major preferred reperfusion strategies to restore the ischemic-related artery patency, but PCI and CABG do not necessarily guarantee the recovery of post-procedure left ventricular (LV) dysfunction and release of symptoms. Moreover, there is no definitive effective way to enhance microcirculations. Theoretically, shock wave therapy (SWT) is an option. We report here a case of patient who received SWT. The patient's medical history was characterized by chest pain for 20 years, having received CABG 13 years ago. The follow-up angiography showed all blood vessels are stiff and rigid therefore no chance for a second CABG. After cardiac SWT treatment for 1 year, the patient's symptoms of chest pain and chronic heart failure significantly improved, the odds of cardiac muscle survival increased, the cardiac remodeling was also improved. What's more, left ventricular ejection fraction (LVEF) was improved from 34% to 51% and 43% in half year and 1 year after SWT which is indicated by single-photon emission computed tomography (SPECT), respectively. To our knowledge, this is the first report of 2-cycle cardiac SWT treatments over 1 year with a complete follow-up, indicating that SWT can not only improve the symptoms of chronic heart failure, but also improve LVEF and cardiac remodeling caused by ischemic cardiomyopathy.
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Bai et al. (2017) conducted a case report in Ischemic cardiomyopathy (n=1). Shock wave therapy (SWT) was evaluated on Left ventricular ejection fraction (LVEF) and cardiac remodeling. Shock wave therapy improved left ventricular ejection fraction from 34% to 43% at 1 year, alongside improvements in chest pain, chronic heart failure symptoms, and cardiac remodeling.
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