Key result
Left ventricular pacing improved LV ejection fraction (+5%, P=0.007) and intraventricular dyssynchrony (-40 ms, P=0.008) to a similar extent as biventricular pacing at 3 months.
Why the study?
Does left ventricular pacing improve clinical and electromechanical outcomes compared to biventricular pacing in patients with chronic heart failure and left bundle branch block?
RCT (n=22)
randomized
Does left ventricular pacing improve clinical and electromechanical outcomes compared to biventricular pacing in patients with chronic heart failure and left bundle branch block?
Left ventricular pacing provides similar mid-term clinical and intraventricular dyssynchrony improvements as biventricular pacing in heart failure patients with LBBB, despite not improving QRS duration.
No takes yet. Share an insight, caveat, or question.
LV pacing matches BiV pacing for LV function gains in HF with LBBB; extends CRT options and warrants larger outcome trials.
Valzania et al. (2007) conducted an RCT in chronic heart failure and left bundle branch block (n=22). Left ventricular pacing vs. Biventricular pacing was evaluated on Clinical and echocardiographic effects (LV ejection fraction and intraventricular dyssynchrony). Left ventricular pacing improved LV ejection fraction (+5%, P=0.007) and intraventricular dyssynchrony (-40 ms, P=0.008) to a similar extent as biventricular pacing at 3 months.