Why the study?
Does treatment of serum samples with 3-mercaptoethanol differentiate between maternally transferred antibodies and antibodies formed by the infant in early infancy Coxsackie B3 infections?
Does treatment of serum samples with 3-mercaptoethanol differentiate between maternally transferred antibodies and antibodies formed by the infant in early infancy Coxsackie B3 infections?
Treatment of serum samples with 3-mercaptoethanol is useful for differentiating maternally transferred antibodies from infant-formed antibodies in early infancy Coxsackie B3 infections.
Answers are grounded in this paper and cite their sources.
May aid serodiagnosis of neonatal Coxsackie B3 infection; hypothesis-generating and requires prospective validation before practice change.
Summary Clinical and virological findings in seven children diseased during early infancy are reported. Serological observations and virus isolations indicated a common etiology (Coxsackie B3 virus) although the clinical picture varied. In the neonatal period respiratory symptoms, most probably of central origin, dominated, whereas in older infants other cerebral symptoms, such as sluggishness or convulsions with unconciousness, were dominant. The diagnostic usefulness of treatment of serum samples with 3‐mercaptoethanol for the differentiation between maternally transferred antibodies and antibodies formed by the infant itself is illustrated and emphasized.
No takes yet. Share an insight, caveat, or question.
Hanson et al. (1966) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: