Key result
Lasp-2 is a newly identified Z-disc scaffolding protein that organizes actin filaments into bundles and interacts directly with alpha-actinin in striated muscle.
Population
Chick and mouse tissue, and primary cultures of chick cardiac and skeletal myocytes
Design
Preclinical
Authors
Loading...
Identifies novel Z-disc scaffolding in striated muscle; leaves open roles in human cardiac or skeletal muscle disorders.
Lasp-2 functions as a scaffolding and actin filament organizing protein within striated muscle Z-discs.
Zieseniß et al. (2007) studied this question. Lasp-2 is a newly identified Z-disc scaffolding protein that organizes actin filaments into bundles and interacts directly with alpha-actinin in striated muscle.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: