Why the study?
Does a single dose of ceftriaxone prevent postoperative infection compared to a 1-day cefazolin regimen in patients undergoing major cardiovascular surgery?
Does a single dose of ceftriaxone prevent postoperative infection compared to a 1-day cefazolin regimen in patients undergoing major cardiovascular surgery?
A single 2 g intravenous dose of ceftriaxone provides reliable antimicrobial prophylaxis comparable to a 1-day cefazolin regimen in cardiovascular surgery, while reducing administration frequency and costs.
No takes yet. Share an insight, caveat, or question.
Single-dose ceftriaxone provides a practical alternative for prophylaxis in cardiovascular surgery; extends evidence supporting simplified regimens with equivalent infection control.
Soteriou et al. (1989) studied this question.
Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context: