Population
Chick embryos during the period between 11 and 22 somites
Design
Preclinical
Authors
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Highlights simultaneous ECG and circulatory onset in chick embryos; extends developmental models but leaves open mammalian translation.
The developmental sequence of the ECG in chick embryos demonstrates that the primitive P wave, QRS complex, blood circulation, and susceptibility to AV block emerge simultaneously at the 17-18 somite stage.
Paff et al. (1968) studied this question.
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