Key result
Major depressive disorder was independently associated with an increased risk of cardiac mortality (HR 1.8; p=0.04) over a median 9.3 years of follow-up after coronary artery bypass graft surgery.
Why the study?
Does depression increase cardiac and all-cause mortality in patients after coronary artery bypass graft surgery?
Population
309 patients hospitalized after coronary artery bypass graft (CABG) surgery
Comparison
Major depressive disorder or elevated depressive… vs Absence of major depressive disorder or elevated…
Design
Cohort
Follow-up
median 9.3 years
Authors
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Depression may warrant screening after CABG; leaves open whether treatment reduces cardiac mortality.
Cohort (n=309)
Does depression increase cardiac and all-cause mortality in patients after coronary artery bypass graft surgery?
Hazard Ratio: 1.8
p-value: p=0.04
Depression assessed before discharge after CABG surgery is an independent predictor of long-term cardiac mortality.
Connerney et al. (2010) conducted a cohort in Coronary artery bypass graft (CABG) surgery (n=309). Major depressive disorder (MDD) vs. No major depressive disorder was evaluated on Cardiac mortality (HR 1.8, p=0.04). Major depressive disorder was independently associated with an increased risk of cardiac mortality (HR 1.8; p=0.04) over a median 9.3 years of follow-up after coronary artery bypass graft surgery.
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