Why the study?
Does ADA isoenzyme analysis accurately diagnose tuberculous pleurisy in patients with pleural effusions?
Population
350 patients with pleural effusions
Design
Cross-sectional
Authors
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ADA-2 at 40 U/L may support tuberculous pleurisy diagnosis in pleural effusions; leaves open prospective validation before clinical adoption.
Does ADA isoenzyme analysis accurately diagnose tuberculous pleurisy in patients with pleural effusions?
High total ADA activity in tuberculous pleural effusions is mainly due to ADA-2, which serves as a highly efficient diagnostic marker for tuberculous pleurisy.
Valdés et al. (1996) studied this question.
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