Key result
The near-infrared fluorescence-labeled long-chain fatty acid Alexa680-BMPP was synthesized to serve as a fluorescent probe for optical imaging of cardiac metabolism in living mice.
Why the study?
A fluorescent probe was needed toward optical imaging of cardiac metabolism in living mice.
The synthesis of Alexa680-BMPP provides a novel fluorescent probe for optical imaging of cardiac metabolism in preclinical mouse models.
May enable preclinical optical imaging of cardiac metabolism; leaves open clinical translation pending validation.
A near infrared fluorescence labelled long-chain fatty acid (FFA), Alexa680-BMPP (BMPP: 15-(4-(3-aminopropyl)phenyl)-3-methyl pentadecanoic acid), was synthesized as a fluorescent probe toward optical imaging of cardiac metabolism.
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Swamy et al. (2022) studied this question. The near-infrared fluorescence-labeled long-chain fatty acid Alexa680-BMPP was synthesized to serve as a fluorescent probe for optical imaging of cardiac metabolism in living mice.
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