Key result
Biventricular pacing significantly decreased QT dispersion (90 ± 12 ms vs 114 ± 22 ms; P<0.01) and T(peak-end) interval compared to baseline sinus rhythm in heart failure patients.
Why the study?
Does biventricular pacing improve ECG markers of ventricular repolarization in patients with congestive heart failure and LBBB compared to sinus rhythm or single-ventricle pacing?
Population
25 patients with congestive heart failure, sinus rhythm, and complete LBBB, mean age 61 +/- 8 years, 6…
Comparison
Permanent biventricular DDDR pacemaker… vs Baseline sinus rhythm, right ventricular pacing…
Design
Cohort
Authors
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Biventricular pacing was associated with reduced repolarization dispersion in HF with LBBB; hypothesis-generating and requires randomized confirmation before practice change.
Does biventricular pacing improve ECG markers of ventricular repolarization in patients with congestive heart failure and LBBB compared to sinus rhythm or single-ventricle pacing?
Absolute Event Rate: 90% vs 114%
p-value: p=<0.01
Biventricular pacing significantly reduces ECG markers of ventricular dispersion of repolarization compared to baseline sinus rhythm or single-ventricle pacing in heart failure patients with LBBB.
Berger et al. (2005) studied Congestive heart failure (n=25). Biventricular pacing vs. Sinus rhythm (baseline) and single-ventricle pacing was evaluated on QT dispersion (p=<0.01). Biventricular pacing significantly decreased QT dispersion (90 ± 12 ms vs 114 ± 22 ms; P<0.01) and T(peak-end) interval compared to baseline sinus rhythm in heart failure patients.
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