Key result
High-sensitivity cardiac troponins can confirm or exclude acute coronary syndrome in a significant proportion of patients with kidney disease, despite altered clearance and baseline elevations.
Why the study?
Early accurate diagnosis of ACS in kidney disease is important, but the diagnostic reliability of cardiac troponins has been suboptimal in acute and chronic kidney impairment.
Does the use of high-sensitivity troponins accurately diagnose acute coronary syndromes in patients with kidney disease?
Population
Patients with acute kidney injury, CKD, and ESKD evaluated for ACS
Design
Review
Authors
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Troponin elevation in CKD complicates ACS diagnosis; leaves open the need for validated kidney-specific thresholds in prospective studies.
Does the use of high-sensitivity troponins accurately diagnose acute coronary syndromes in patients with kidney disease?
Despite altered clearance and chronic elevations in kidney disease, high-sensitivity troponins can effectively confirm or exclude ACS in a significant proportion of these patients.
Banerjee et al. (2019) conducted a review in Acute coronary syndrome and kidney disease. Cardiac troponins was evaluated. High-sensitivity cardiac troponins can confirm or exclude acute coronary syndrome in a significant proportion of patients with kidney disease, despite altered clearance and baseline elevations.
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