Population
Foot-and-Mouth Disease Virus
Comparison
Disruption with 8m-urea and treatment with trypsin vs Untreated virus
Design
Preclinical
Authors
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Supports a trypsin-sensitive polypeptide in FMDV attachment and immunogenicity; leaves open its vaccine potential pending further studies.
A specific polypeptide on the surface of the foot-and-mouth disease virus is necessary for cell attachment and immunizing activity.
Wild et al. (1969) studied this question.
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