Why the study?
Does repeated vaccination with formalin- or AEI-inactivated FMD vaccines induce VIA antibodies in cattle?
Population
48 Devon steers, 18-24 months old, housed in disease-secure isolation units.
Design
Preclinical
Follow-up
Up to 213 days
Authors
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May confound FMD infection diagnosis in vaccinated cattle; leaves open differential effects of formalin versus AEI vaccines.
Does repeated vaccination with formalin- or AEI-inactivated FMD vaccines induce VIA antibodies in cattle?
Repeated vaccination with inactivated FMD vaccines can induce VIA antibodies in cattle, indicating that the presence of VIA antibodies is not conclusive proof of natural infection.
Pinto et al. (1979) studied this question.
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