Key result
Human coronavirus was detected in 2.25% of patients with acute respiratory symptoms, with OC43 being the most prevalent, and HCoV infection was associated with increased odds of hospital admission (OR 3.17).
Population
13,048 adults and children with fever and acute upper respiratory infection symptoms in Guangzhou, south…
Design
Cross-sectional
Authors
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Does not support changing respiratory testing protocols; leaves open HCoV's independent prognostic role.
Observational (n=13,048)
Yes
Odds Ratio: 3.17 (95% CI 2.29–4.39)
HCoV-OC43, particularly the newly defined genotype G, was the dominant human coronavirus strain causing respiratory infections in Guangzhou from 2010-2015.
Zhang et al. (2018) conducted an observational in Acute respiratory infection (n=13,048). Human coronavirus (HCoV) infection vs. Non-HCoV respiratory infection was evaluated on Severe disease or hospital admission (OR 3.17, 95% CI 2.29-4.39). Human coronavirus was detected in 2.25% of patients with acute respiratory symptoms, with OC43 being the most prevalent, and HCoV infection was associated with increased odds of hospital admission (OR 3.17).
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