Why the study?
Does high-dose aspirin reduce the incidence of coronary aneurysms compared to medium- or low-dose aspirin in children with Kawasaki syndrome?
Population
110 children having 113 attacks of Kawasaki syndrome in Manhattan, New York. Age at onset 7 weeks to 12…
Comparison
High-dose aspirin until afebrile, then 81 mg… vs Medium- or low-dose aspirin
Design
Cohort
Follow-up
1 month
Authors
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No difference by aspirin dose; leaves open optimal dosing in Kawasaki disease pending randomized trials.
Does high-dose aspirin reduce the incidence of coronary aneurysms compared to medium- or low-dose aspirin in children with Kawasaki syndrome?
In children with Kawasaki syndrome, high-dose aspirin did not significantly reduce the incidence of coronary aneurysms compared to medium- or low-dose aspirin.
Ichida et al. (1987) studied this question.
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