Key result
Melatonin demonstrates favorable effects on the cardiovascular system through its antioxidant properties, regulation of lipid and glucose metabolism, and reduction of blood pressure.
Why the study?
Although studies show favorable cardiovascular effects of melatonin, it has not taken its rightful place in clinical practice.
Does melatonin improve cardiovascular disease and its risk factors?
Does melatonin improve cardiovascular disease and its risk factors?
Melatonin is a promising supplement with favorable effects on cardiovascular risk factors and disease progression, warranting further large-scale prospective human trials.
Answers are grounded in this paper and cite their sources.
Melatonin may modulate CAD inflammation; leaves open clinical adoption pending RCTs.
Coronary artery disease (CAD) is one of the leading causes of morbidity and mortality worldwide. The coronary atherosclerotic process involves different pathological mechanisms; inflammation is one of the major triggers for the development of atherosclerotic plaque. Although several studies showed the favorable effects of melatonin on the cardiovascular system (CVS), melatonin seems not to take its rightful place in today's clinical practice. This review aims to point out the role of melatonin on cardiovascular disease (CVD) and its' risk factors. All data were obtained via PubMed, Wikipedia, and Google.
No takes yet. Share an insight, caveat, or question.
Özkalaycı et al. (2021) conducted a review in Cardiovascular Disease. Melatonin was evaluated. Melatonin demonstrates favorable effects on the cardiovascular system through its antioxidant properties, regulation of lipid and glucose metabolism, and reduction of blood pressure.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: