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August 17, 2025Current Issues in Molecular BiologyOpen Access

Circadian Rhythm Disruptions and Cardiovascular Disease Risk: The Special Role of Melatonin

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Authors

JNJarosław NuszkiewiczNicolaus Copernicus UniversityWRWojciech RzepkaNicolaus Copernicus UniversityJMJulia MarkielNicolaus Copernicus University

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Implication

Narrative review highlights links between circadian disruptions and cardiovascular disease risk, suggesting melatonin supplementation may aid in recovery.

Key Points

  • Circadian rhythm disruptions increase cardiovascular disease risk, emphasizing the importance of maintaining regular biological cycles.
  • Key evidence shows that melatonin can mitigate factors like oxidative stress and inflammation linked to cardiovascular issues.
  • This narrative review synthesizes findings on melatonin's role in restoring circadian alignment and cardiovascular health.
  • Chronotherapeutic strategies remain underutilized, indicating the need for practical biomarker development and improved clinical integration.

Cite This Study

Nuszkiewicz et al. (2025) studied this question.

synapsesocial.com/papers/68af475aad7bf08b1ead42echttps://doi.org/10.3390/cimb47080664
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