Why the study?
Does BMI ≥ 25.0 kg/m² increase the incidence of cardiovascular disease compared to BMI 23.0–<25.0 kg/m²?
Does BMI ≥ 25.0 kg/m² increase the incidence of cardiovascular disease compared to BMI 23.0–<25.0 kg/m²?
The population-attributable fraction of overweight/obesity for CVD incidence has significantly increased in Japan over recent decades, largely mediated by hypertension.
Overweight/obesity is a determinant of hypertension, together with high sodium and alcohol intake or low physical activity 1) . It was reported that hypertension without being overweight used to constitute a majority of the hypertension cases in Japanese rural communities in 1960's but not in 1980's 2) . This change was accompanied by increases in overweight/obesity and the proportion of hypertension among the overweight/obesity 2, 3) . Even after 1980's, increase in the attribute of overweight/obesity to hypertension has been reported in Japan or China Since hypertension continues to be the leading risk factor for cardiovascular diseases (CVDs) with or without overweigh/obesity 6) , increases in the prevalence of overweight/obesity and the fraction of hypertension attributable to overweight/obesity suggest an increasing role of overweight/obesity in determining the magnitude of CVD risk.
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Hiroshi Yatsuya (2022) conducted an editorial in Hypertension and Cardiovascular Diseases. Overweight/obesity (BMI ≥ 25.0 kg/m2) vs. BMI 23.0-25.0 kg/m2 was evaluated on Incidence of cardiovascular disease.
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