A baseline BMI ≥25.0 was associated with a higher risk of incident hypertension compared to a BMI <19.0, with hazard ratios ranging from 1.29 to 1.47 across age and sex groups.
Why the study?
Does baseline BMI ≥ 25.0 increase the risk of incident hypertension compared to BMI < 19.0 in nonhypertensive Japanese adults?
Population
68,205 nonhypertensive adults aged 40-79 years who completed health check-ups in the Ibaraki prefecture, Japan
Comparison
BMI ≥ 25.0 vs BMI < 19.0
Design
Cohort
Follow-up
mean 3.9 years
Key result
A baseline BMI ≥25.0 was associated with a higher risk of incident hypertension compared to a BMI <19.0, with hazard ratios ranging from 1.29 to 1.47 across age and sex groups.
Authors
Discussion
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Overview
May inform risk assessment in nonhypertensive Japanese adults; leaves open whether weight loss prevents incident hypertension.
Study Design
Type
Cohort (n=68,205)
Structured PICO
Does baseline BMI ≥ 25.0 increase the risk of incident hypertension compared to BMI < 19.0 in nonhypertensive Japanese adults?
P
Population
68,205 nonhypertensive adults aged 40-79 years in Japan, followed for a mean of 3.9 years to assess the risk of incident hypertension.
E
Exposure
BMI ≥ 25.0
C
Comparator
BMI < 19.0
O
Outcome
Incident hypertension (defined as SBP ≥ 140 mmHg, DBP ≥ 90 mmHg, and/or hypertensive medication use)surrogate
Main Result
Hazard Ratio: 1.42 (95% CI 1.17–1.73)
Baseline BMI ≥ 25.0 is significantly associated with an increased risk of incident hypertension in Japanese adults, independent of weight change during follow-up.
Cite This Study
Tsujimoto et al. (2012) conducted a cohort in Nonhypertensive (n=68,205). BMI ≥25.0 vs. BMI <19.0 was evaluated on Incident hypertension (SBP ≥140 mmHg, DBP ≥90 mmHg, and/or hypertensive medication use) (HR 1.42, 95% CI 1.17-1.73). A baseline BMI ≥25.0 was associated with a higher risk of incident hypertension compared to a BMI <19.0, with hazard ratios ranging from 1.29 to 1.47 across age and sex groups.