Why the study?
The study was conducted to assess the influence of different age groups on the spread of hand, foot and mouth disease.
Mathematical modeling of HFMD in China highlights that children under three are at high risk and adults in contact with them play a crucial role in disease transmission.
Highlights targeted prevention for children under 3 and adult contacts; leaves open real-world validation of transmission estimates.
In order to access the influence of different age groups on the spread of hand, foot and mouth disease (HFMD), we established the multi-group model with migration following the epidemiology of HFMD. The basic reproduction number of the HFMD epidemic model was calculated by the next generation operator method. According to China's national surveillance data on HFMD, we fitted the model parameters and estimated the transmission rates among different age groups. Besides, we carried out sensitivity analysis for the basic reproduction number to find some valuable regulatory measures. Our findings showed that the children under three years of age were indeed at high risk and adult group who had more contacts with children had a crucial influence on the spread of HFMD.
No takes yet. Share an insight, caveat, or question.
Li et al. (2019) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: