Key result
From 2016 to 2018 in Hangzhou, other enteroviruses (predominantly CV-A6) replaced EV71 as the major cause of hand, foot and mouth disease, accounting for over 80% of confirmed cases.
Why the study?
The study was conducted to determine the epidemiological characteristics of hand, foot and mouth disease and the relationship between severe and mild disease in Hangzhou.
Observational (n=4,760)
No
The epidemiological profile of HFMD in Hangzhou has shifted, with non-EV71/non-CV-A16 enteroviruses becoming the predominant pathogens, emphasizing the need for updated surveillance and multivalent vaccines.
Authors
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Observational HFMD data in Chinese children; leaves open serotype-severity links for prospective confirmation.
Wang et al. (2019) conducted an observational in Hand, foot and mouth disease (HFMD) (n=4,760). Enterovirus infection (EV71, CV-A16, and other EVs) was evaluated on Pathogen distribution among confirmed enterovirus-positive HFMD cases. From 2016 to 2018 in Hangzhou, other enteroviruses (predominantly CV-A6) replaced EV71 as the major cause of hand, foot and mouth disease, accounting for over 80% of confirmed cases.
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