What question did this study set out to answer?

To evaluate the total phenolic content, antioxidant capacity, and cytotoxic effects of extracts from ten edible flower species on human cancer and non-tumorigenic cell lines.

August 1, 2013Open Life SciencesOpen Access

Edible flowers — antioxidant activity and impact on cell viability

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Authors

ZKZdenka KucekováTomas Bata University in Zlín JMJiří MlčekTomas Bata University in Zlín PHPetr HumpolíčekTomas Bata University in Zlín

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Implication

In vitro study demonstrates differential cell viability modulation in human cell lines, suggesting potential therapeutic application for edible flower extracts.

Key Points

To evaluate the total phenolic content, antioxidant capacity, and cytotoxic effects of extracts from ten edible flower species on human cancer and non-tumorigenic cell lines.
Extracted and quantified total phenolic content and antioxidant activity across ten edible flower species: Allium schoenoprasum, Bellis perennis, Cichorium intybus, Rumex acetosa, Salvia pratensis, Sambucus nigra, Taraxacum officinale, Tragopogon pratensis, Trifolium repens, and Viola arvensis.
Assessed cell viability after a 3-day incubation with flower extracts at 25, 50, 75, and 100 μg/ml of total phenolic compounds using colorimetric MTT assays in human hepatocellular carcinoma (HepG2) and non-tumorigenic keratinocyte (HaCaT) lines.
Total phenolic content spanned from 11.72 to 42.74 mg of tannin equivalents/kg of dry matter, and antioxidant activity ranged between 35.56 and 71.62 g of ascorbic acid equivalents/kg of dry matter.
Extracts produced significant effects on cell viability that varied by flower species, phenolic concentration, and overall antioxidant profile, eliciting divergent responses between cancerous HepG2 and non-tumorigenic HaCaT cells.

Cite This Study

Kuceková et al. (2013) studied this question.

synapsesocial.com/papers/6a6f6071febe604dd7084f73 https://doi.org/10.2478/s11535-013-0212-y

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Implication

In vitro study demonstrates differential cell viability modulation in human cell lines, suggesting potential therapeutic application for edible flower extracts.

Edible flowers — antioxidant activity and impact on cell viability

Discussion

Member takes

Implication

Key Points

Cite This Study

Edible flowers — antioxidant activity and impact on cell viability

Discussion

Member takes

Implication

Key Points

Cite This Study

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