Subtle changes in renal function are associated with differences in late survival following adult cardiac surgery
Population
8,032 adult patients who underwent coronary artery bypass grafting, valve surgery, or combined procedures…
Design
Cohort
Follow-up
median 72 months (IQR 48-105)
Authors
Discussion
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Member takes
Implication
Day 4 eGFR may refine late survival prediction after cardiac surgery; leaves open its role in guiding management pending prospective validation.
Structured PICO
P
Population
8,032 adult patients who underwent coronary artery bypass grafting, valve surgery, or combined procedures, who did not require preoperative renal replacement therapy.
O
Outcome
Late survival (late deaths) at median 72 months follow-uphard clinical
Subtle early changes in renal function, specifically day 4 post-operative eGFR, are powerful independent predictors of late survival following adult cardiac surgery.
Cite This Study
Howell et al. (2012) studied this question.