Why the study?
Does intravenous immunoglobulin improve clinical and laboratory recovery in young men with acute myocarditis indicating poor prognosis?
Does intravenous immunoglobulin improve clinical and laboratory recovery in young men with acute myocarditis indicating poor prognosis?
Intravenous immunoglobulin may aid in the rapid recovery of acute myocarditis with poor prognosis when added to conventional therapy.
Hypothesis-generating for IVIG in poor-prognosis acute myocarditis; prospective trials needed before clinical adoption.
Two cases of acute myocarditis in young men, both with clinical and laboratory criteria indicating poor prognosis, were initially treated with conventional treatment (captopril plus metoprolol). The addition of intravenous immunoglobulin was followed by rapid clinical and laboratory recovery. This observation is considered to support previous but ambiguous evidence that autoimmune treatment may help recovery from acute myocarditis that has evidence of poor prognosis.
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Eleftheriou et al. (2009) studied this question.
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