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April 1, 1978CirculationOpen Access

Verapamil in the management of supraventricular tachyarrhythmias occurring after a recent myocardial infarction.

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Why the study?

Does intravenous verapamil improve reversion to sinus rhythm or rate control in patients with supraventricular tachyarrhythmias after a recent myocardial infarction?

Population

16 patients with a sustained supraventricular tachyarrhythmia occurring less than 72 hours after the first…

Design

Case_series

Authors

FHF HagemeijerFund for Scientific Research

Discussion

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Implication

May support verapamil for post-MI rate control; leaves open confirmation of rhythm conversion in randomized trials.

Structured PICO

Does intravenous verapamil improve reversion to sinus rhythm or rate control in patients with supraventricular tachyarrhythmias after a recent myocardial infarction?

P
Population
16 patients with a sustained supraventricular tachyarrhythmia (8 with atrial flutter, 8 with atrial fibrillation) occurring less than 72 hours after the first symptom of an acute myocardial infarction.
I
Intervention
Verapamil given intravenously in 1 mg increments every minute (maximum dose 20 mg) under continuous monitoring.
O
Outcome
Reversion to sinus rhythm or a ventricular rate slower than 100/min.surrogate

Intravenous verapamil is effective for acute rate control and rhythm conversion of supraventricular tachyarrhythmias, particularly atrial flutter, early after acute myocardial infarction.

Cite This Study

F Hagemeijer (1978) studied this question.

synapsesocial.com/papers/6a6f74a4ac440176ef28224fhttps://doi.org/10.1161/01.cir.57.4.751
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1A fourth class of anti-dysrhythmic action? Effect of verapamil on ouabain toxicity, on atrial and ventricular intracellular potentials, and on other features of cardiac function1972 · 291 citations
  2. 2Effect of verapamil on contractility, oxygen utilization, and calcium exchangeability in mammalian heart muscle1972 · 209 citations
  3. 3CLINICAL EXPERIENCE WITH VERAPAMIL1975 · 14 citations
  4. 4Verapamil in the treatment of paroxysmal supraventricular tachycardia1974 · 195 citations
  5. 5Verapamil induced premature ventricular beats before reversion of supraventricular tachycardia.1974 · 32 citations