Why the study?
Does poor glycemic control in pre-gestational diabetic pregnancies impair fetal cardiac function compared to well-controlled pregnancies?
Population
21 pregnant women with type 1 pre-gestational diabetes enrolled at 30-32 weeks gestation
Comparison
Poorly-controlled diabetes (HbA1c > 6.5%) vs Satisfactorily controlled diabetes (HbA1c ≤ 6.5%)
Design
Cross-sectional
Authors
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May indicate early fetal cardiac changes in poorly controlled diabetes; hypothesis-generating and requires prospective validation before practice implications.
Does poor glycemic control in pre-gestational diabetic pregnancies impair fetal cardiac function compared to well-controlled pregnancies?
Fetuses of poorly-controlled diabetic mothers exhibit a lower right atrioventricular E/A ratio, suggesting potential early non-hypertrophic cardiac dysfunction.
Wong et al. (2003) studied this question.
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