Key result
Maternal well-controlled type I diabetes was associated with significant augmentation of fetal interventricular septal thickness, but did not affect fetal cardiac function compared to controls.
Why the study?
Does well-controlled maternal type I diabetes affect fetal cardiac development and performance compared to normal pregnancies?
Observational
Does well-controlled maternal type I diabetes affect fetal cardiac development and performance compared to normal pregnancies?
Well-controlled maternal type I diabetes is associated with progressive, mild fetal myocardial thickening that does not impair fetal cardiac function.
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Supports serial fetal echocardiography in T1DM; leaves open long-term postnatal cardiac implications.
Jaeggi et al. (2001) conducted an observational in Maternal type I diabetes. Maternal type I diabetes vs. Age-matched normal fetuses was evaluated on Fetal cardiac development and performance (interventricular septal thickness, valve diameters, flow velocities, fractional shortenings, output). Maternal well-controlled type I diabetes was associated with significant augmentation of fetal interventricular septal thickness, but did not affect fetal cardiac function compared to controls.
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