October 1, 1972The Journal of PhysiologyOpen Access

Reflex firing in the lumbar sympathetic outflow to activation of vesical afferent fibres*

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Population

Cats with an intact spinal cord and acute and chronic spinal animals (transections at T10-T12)

Design

Preclinical

Authors

WGWilliam C. de GroatJikei University School of Medicine PLPeter M. LalleyUniversity of Wisconsin–Madison

Discussion

Member takes

Implication

Reveals dual excitatory and inhibitory lumbar sympathetic reflexes to bladder afferents; leaves open translation to human voiding disorders.

Structured PICO

Population

Cats with an intact spinal cord and acute and chronic spinal animals (transections at T10-T12)

Intervention

Activation of vesical afferent fibres in the Agammadelta range by electrical stimulation of the pelvic nerve or by bladder distension

Outcome

Reflex firing in hypogastric nerves and in preganglionic nerves to the inferior mesenteric ganglionsurrogate

The study demonstrates that lumbar sympathetic outflow to the bladder involves both excitatory and inhibitory reflex pathways in response to vesical afferent activation.

Cite This Study

Groat et al. (1972) studied this question.

synapsesocial.com/papers/6a6f7a07f44fa9f079dcec22 https://doi.org/10.1113/jphysiol.1972.sp009985

View Full Paper

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Implication

Reveals dual excitatory and inhibitory lumbar sympathetic reflexes to bladder afferents; leaves open translation to human voiding disorders.

Reflex firing in the lumbar sympathetic outflow to activation of vesical afferent fibres*

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Reflex firing in the lumbar sympathetic outflow to activation of vesical afferent fibres*

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider