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Coronavirus disease 2019 (COVID-19) is an emerging human infectious disease caused by a novel β coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Clinical manifestations range from asymptomatic infection, self-limited flu-like symptoms, to severe acute pneumonia with high mortality. Whereas the lung is the primary target in this pandemic disease, other organs can be affected, including the gastrointestinal tract, liver, heart, blood, and kidneys.1 Acute respiratory distress syndrome and multiorgan damage, which are responsible for most mortalities, are thought to be mediated by an acute release of inflammatory cytokines, representing cytokine release syndrome.
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Nasr et al. (2020) studied this question.
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