What question did this study set out to answer?

To evaluate the frequency of acute respiratory and nonrespiratory diagnoses among adults hospitalized with laboratory-confirmed influenza.

March 20, 2020JAMA Network OpenOpen Access

Respiratory and Nonrespiratory Diagnoses Associated With Influenza in Hospitalized Adults

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Authors

ECEric J. ChowAssociation of Public Health Laboratories MRMelissa A. RolfesCenters for Disease Control and Prevention AOAlissa O’HalloranCenters for Disease Control and Prevention

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Implication

Cross-sectional study reveals frequent nonrespiratory diagnoses like sepsis and kidney injury in adults hospitalized with influenza, highlighting the need for broader clinical testing.

Key Points

To evaluate the frequency of acute respiratory and nonrespiratory diagnoses among adults hospitalized with laboratory-confirmed influenza.
Cross-sectional surveillance study using data from the multicenter US Influenza Hospitalization Surveillance Network (FluSurv-NET) across the 2010–2011 through 2017–2018 seasons.
Included N=76,649 hospitalized adults (aged ≥18 years; median age 69 years) with laboratory-confirmed influenza by RT-PCR, rapid antigen testing, fluorescent staining, or viral culture and acute ICD-9/10 discharge codes.
Acute respiratory diagnoses occurred in 94.9% of patients, whereas 46.5% had nonrespiratory diagnoses and 5.1% had only nonrespiratory diagnoses.
The most common acute conditions were pneumonia (36.3%), sepsis (23.3%), and acute kidney injury (20.2%).
Patients with exclusively nonrespiratory diagnoses received antiviral therapy significantly less often than those with respiratory diagnoses (81.4% vs 88.9%, P < .001).

Cite This Study

Chow et al. (2020) studied this question.

synapsesocial.com/papers/6a6f7cb9439bab0cabc2cf71 https://doi.org/10.1001/jamanetworkopen.2020.1323

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Implication

Cross-sectional study reveals frequent nonrespiratory diagnoses like sepsis and kidney injury in adults hospitalized with influenza, highlighting the need for broader clinical testing.

Respiratory and Nonrespiratory Diagnoses Associated With Influenza in Hospitalized Adults

Discussion

Member takes

Implication

Key Points

Cite This Study

Respiratory and Nonrespiratory Diagnoses Associated With Influenza in Hospitalized Adults

Discussion

Member takes

Implication

Key Points

Cite This Study

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