Why the study?
Does successful weight reduction improve left ventricular diastolic function and physical performance in severely obese subjects?
Population
188 obese subjects, including 71 with left ventricular diastolic dysfunction at baseline.
Comparison
Successful weight reduction following a 1-year… vs Failed weight reduction following the same…
Design
Cohort
Follow-up
1 year
Authors
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Supports weight loss for LVDD and capacity in severe obesity; hypothesis-generating, needs RCT confirmation.
Does successful weight reduction improve left ventricular diastolic function and physical performance in severely obese subjects?
In severe obesity, successful long-term weight reduction of at least 8% is associated with significant improvements in left ventricular diastolic function and exercise capacity.
Fenk et al. (2015) studied this question.
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