Why the study?
Does lifestyle modification improve vascular and ventricular function and structure in obese subjects?
Population
50 subjects total: 39 obese subjects and 11 healthy weight controls. 17 of the obese subjects completed a…
Comparison
Lifestyle modification treatment for 4-9 months vs Healthy weight controls and pre-intervention…
Design
Cohort
Follow-up
4-9 months
Authors
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Moderate weight loss may not reverse obesity-linked vascular changes; hypothesis-generating for longer-term trials before practice implications.
Does lifestyle modification improve vascular and ventricular function and structure in obese subjects?
While obesity is associated with adverse cardiac and vascular structural changes, moderate short-term weight loss via lifestyle modification improves serum biomarkers but does not reverse these structural changes.
Skilton et al. (2007) studied this question.
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