Key result
Weight reduction via gastroplasty in patients with obesity significantly improved left ventricular diastolic filling (P<0.001) and ejection fraction (P<0.01) compared to dietary controls at 1 year.
Why the study?
Does weight-reducing gastroplasty improve cardiac function and valvular performance in patients with obesity compared to dietary recommendations?
Population
115 subjects, comprising 41 patients with obesity referred for weight-reducing gastroplasty, 31 patients…
Comparison
Weight-reducing gastroplasty vs Dietary recommendations and lean subjects
Design
Cohort
Follow-up
1 year
Authors
Loading...
Gastroplasty-linked weight loss may improve LV filling and EF in obesity; leaves open superiority over diet in randomized trials.
Cohort (n=115)
Does weight-reducing gastroplasty improve cardiac function and valvular performance in patients with obesity compared to dietary recommendations?
p-value: p=<0.001
Surgical weight loss in obese patients is associated with significant improvements in left ventricular diastolic filling and ejection fraction without promoting valvular heart disease.
Karason et al. (1998) conducted a cohort in Obesity (n=115). Weight-reducing gastroplasty vs. Dietary recommendations (obese control) and lean subjects was evaluated on Echocardiographic measures of cardiac function (E/A ratio and LVEF) (p=<0.001). Weight reduction via gastroplasty in patients with obesity significantly improved left ventricular diastolic filling (P<0.001) and ejection fraction (P<0.01) compared to dietary controls at 1 year.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: