Potential Prognostic Value of Native T1 in Pulmonary Hypertension Patients

Figures

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  Figure 1. Late gadolinium enhancement (LGE), volumetric, and parametric mapping measurements were obtained with similar workflows. The number of planes obtained and the traced regions differed for each analysis (Reprinted with permission from Ref. [10]. 2022, John W. Cerne).

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  Figure 2. Flow-chart detailing excluded data.

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  Figure 3. Receiver-operating characteristic curves of left ventricle and right ventricle ejection fractions (LVEFs and RVEFs, respectively) within Pre-Capillary Component and Isolated Post-Capillary pulmonary hypertension (PH) patients. The binary classifier was the occurrence of a cardiac event within 2 years of cardiac MRI. RVEF showed a statistically significant classification ability within Pre-Capillary Component PH patients. * = p < 0.05.

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  Figure 4. Box-plot comparisons of native T1, extracellular volume fraction (ECV), and late gadolinium enhancement (LGE) between Pre-Capillary Component pulmonary hypertension (PreCompPH) and Isolated Post-Capillary pulmonary hypertension (IpcPH) patients. Mann-U Whitney Tests or Independent Samples t-Tests were used based on normality testing by Shapiro–Wilk Test (p < 0.05 or p > 0.05, respectively). * = p < 0.05.

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  Figure 5. Receiver-operating characteristic curves of native T1 within Pre-Capillary Component and Isolated Post-Capillary pulmonary hypertension (PH) patients. The binary classifier was the occurrence of a cardiac event within 2 years of cardiac MRI.

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  Figure 6. Kaplan–Meier survival curves were used to compare patients with native T1 values < 1050 ms and >1050 ms within Pre-Capillary Component pulmonary hypertension (PH) and Isolated Post-Capillary pulmonary hypertension (PH) patient groups. * = p < 0.05.