Population
Rat vascular smooth muscle cells
Comparison
Angiotensin II (10(-10) to 10(-6) mol/L) vs Control/unstimulated cells and cells treated…
Design
Preclinical
Authors
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Extends AT1-IL-6 mechanistic data in rodents; leaves open human relevance to atherosclerosis.
Angiotensin II induces proinflammatory IL-6 expression in rat vascular smooth muscle cells via the AT1 receptor, providing insight into its role in atherogenesis.
Funakoshi et al. (1999) studied this question.
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