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Inherited factor XI deficiency links to variable bleeding risk, typically manifesting after trauma or surgery.
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Inherited factor XI (FXI) deficiency, also called Hemophilia C, is an uncommon autosomal recessive disorder, which is associated with a variable bleeding tendency that usually manifests after trauma or surgery. This concise report reviews current knowledge regarding the pathogenesis, genetics, diagnosis, clinical manifestations and management of this inherited bleeding disorder.
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Franchini et al. (2006) studied this question. Inherited factor XI deficiency is an uncommon autosomal recessive disorder associated with a variable bleeding tendency that typically manifests after trauma or surgery.
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