New Anticoagulants for the Cardiovascular Patient

Cardiovascular patients undergoing invasive cardiac procedures and cardiac surgery, particularly those with difficult to control perioperative bleeding, heparin-induced thrombocytopenia, allergic reactions to protamine, platelet dysfunction, or poor response to heparin.

Blood preservation protocols and alternative anticoagulants including hirudin, hirulog, iloprost, ancrod, Lomoparan, low-molecular-weight heparins, 1-deamino-8-D-arginine-vasopressin (DDAVP), and aprotinin.