Why the study?
What is the prevalence of QTc prolongation and ventricular arrhythmias among hospitalized patients on methadone therapy?
Population
291 hospitalized patients on methadone therapy in an inner-city urban community
Design
Cohort
Authors
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QTc prolongation occurs frequently during methadone therapy in hospitalized patients; this cohort study leaves open the contribution of dose and drug interactions to ventricular arrhythmia risk.
What is the prevalence of QTc prolongation and ventricular arrhythmias among hospitalized patients on methadone therapy?
Hospitalized patients on methadone frequently experience QTc prolongation, especially when taking concurrent interacting drugs, though ventricular arrhythmias remain relatively uncommon.
Chowdhury et al. (2015) studied this question.
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