Anemia in Hodgkin's disease

A .Hodgkin's disease.1:t is present in approximately one third to one half of patients on their initial hospital admission111 1 7 and eventually develops in alrnost all cases.In occasional patients, the anemia can be related to blood loss, uremia, inrection, or to treatment with myelosuppres.siveagents.In the majority of instances, however, anemia appears to be related solely to the primary malignant process.The 2 priincipal pathogenetic mechanisms that have been described are hemolysis and abnormalities in the utilization of iron for erythropoiesis.A shortened erythrocyte survival in Hodgkin's disease is a frequent finding.Sl9918 The