Why the study?
Does an integrated host gene expression diagnostic model accurately discriminate between bacterial and viral infections in patients with acute infections?
Does an integrated host gene expression diagnostic model accurately discriminate between bacterial and viral infections in patients with acute infections?
An integrated host gene expression model can accurately discriminate between bacterial and viral infections, potentially guiding appropriate early antibiotic use.
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May aid early antibiotic decisions via compact gene signature; leaves open prospective validation before clinical adoption.
Sweeney et al. (2016) studied this question.