What question did this study set out to answer?

To review effective management strategies, diagnostic challenges, and emerging pharmacologic and nonpharmacologic treatments for chronic constipation.

September 1, 2023Current Opinion in Gastroenterology

Step on the accelerator: modern treatment of constipation

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Authors

DSDaniel StaurskyAugusta University DSDhanush ShimogaAugusta University ASAmol SharmaMedical University of South Carolina

Discussion

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Implication

Review reveals high dissatisfaction with standard constipation therapies across gastrointestinal conditions, highlighting emerging targeted drugs and vibrating capsules as effective alternatives.

Key Points

To review effective management strategies, diagnostic challenges, and emerging pharmacologic and nonpharmacologic treatments for chronic constipation.
Narrative review synthesizing clinical evidence on conservative, over-the-counter, pharmacologic, and device-based interventions for constipation.
Fewer than 20% of patients report satisfaction with constipation treatment, and over 60% report dissatisfaction with over-the-counter therapies.
Severe to very severe constipation occurs in 60% of patients with functional dyspepsia and gastroparesis, correlating directly with upper gastrointestinal symptom severity.
Consuming two gold kiwifruits is noninferior to 10 g of psyllium, while emerging interventions including GCC agonists, NHE3 inhibitors, and vibrating capsules demonstrate therapeutic promise.

Cite This Study

Staursky et al. (2023) studied this question.

synapsesocial.com/papers/6a6f8e8a5d37378ac1dc9d45 https://doi.org/10.1097/mog.0000000000000982

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Implication

Review reveals high dissatisfaction with standard constipation therapies across gastrointestinal conditions, highlighting emerging targeted drugs and vibrating capsules as effective alternatives.

Step on the accelerator: modern treatment of constipation

Discussion

Member takes

Implication

Key Points

Cite This Study

Step on the accelerator: modern treatment of constipation

Discussion

Member takes

Implication

Key Points

Cite This Study

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